Brain abscess by citrobacter diversus in infancy: case report.

Neonatal citrobacter meningitis: neurosonographic observations.

Meningitis caused by gram-negative enteric bacteria usually is limited in children to the neonatal period. Among neonates, the disease is severe, with a mortality of up to 80%. The most common etiologic agent in this type of meningitis is Escherichia coli. Meningitis due to Citrobacter diversus has occurred in sporadic small outbreaks throughout the United States. This devastating disease frequ...

Pathophysiology of Citrobacter diversus neonatal meningitis: comparative studies in an infant mouse model.

Citrobacter diversus is a cause of devastating neonatal meningitis, with illness characterized by formation of multiple brain abscesses. We developed an infant mouse intracranial inoculation model to evaluate the pathophysiology of C. diversus neonatal infections. Eighteen of 26 strains inoculated intracranially at a dose of ca. 3.3 x 10(3) CFU caused greater than 50% mortality in 2-day-old mic...

Fulminant citrobacter meningitis with multiple periventricular abscesses in a three-month-old infant.

Citrobacter, a Gram-negative enteric bacillus, is a rare cause of septicemia and meningitis, seldom reported beyond the neonatal period. It is characterized by a fulminant clinical course and a high incidence of complications, including brain abscesses. We studied a three-month-old infant with Citrobacter meningitis, who developed acute communicating hydrocephalus and multiple periventricular b...

The role of Citrobacter in clinical disease of children: review.

Various species of Citrobacter may cause infections in neonates and immunocompromised hosts. Citrobacter koseri (formerly Citrobacter diversus) is best known as the cause of sepsis and meningitis leading to central nervous system (CNS) abscesses in neonates and young infants. Early onset and late-onset infections occur as for other neonatal bacterial infections. The majority of cases are sporad...

Brain abscesses in neonatal Citrobacter diversus meningitis SWISS SOCIETY OF NEONATOLOGY